It is recommended for use in domestic animals as an aid in preventing and treating tetanus.
Recommended for use when a nonimmunized animal, or one whose immune status is unknown, suffers a deep penetrating wound that has or may become contaminated with soil. It provides quick, short-term protection. The antitoxin may also be administered to animals following castration, docking, and other operations performed on premises upon which tetanus infection has been a problem.
Confers immediate passive immunity lasting about 7-14 days. 1,500 units administered subcutaneously or intramuscularly is the recommended dose for prevention.
Large doses may provide a beneficial response in animals already infected with tetanus but the success of the treatment is not ensured. For treatment administer 10,000 to 50,000 units to horses and cattle and 3,000 to 15,000 units to sheep and swine. Animals that suffer slow healing puncture wounds or deep abrasions should be given a second dose of antitoxin in 7 days and additionally as considered necessary.
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